英文名稱 | Ruscogenin |
---|---|
中文名稱 | 魯斯可皂苷元 | 螺可吉寧 |
CAS號 | 472-11-7 |
分子式 | C27H42O4 |
分子量 | 430.62 |
外觀 | White to off-white powder |
儲存條件 | 4°C, protect from light |
英文名稱 | Ruscogenin |
---|---|
中文名稱 | 魯斯可皂苷元 | 螺可吉寧 |
CAS號 | 472-11-7 |
分子式 | C27H42O4 |
分子量 | 430.62 |
外觀 | White to off-white powder |
儲存條件 | 4°C, protect from light |
Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity.
PMID: 27589720 PMCID: PMC5037697 DOI: 10.3390/ijms17091418
PMID: 18946195 DOI: 10.1254/jphs.08083fp