英文名稱 | Scutebarbatine A |
---|---|
中文名稱 | 半枝蓮堿A |
CAS號 | 176520-13-1 |
分子式 | C32H34N2O7 |
分子量 | 558.62 |
外觀 | White to off-white powder |
儲存條件 | 20°C, protect from light |
英文名稱 | Scutebarbatine A |
---|---|
中文名稱 | 半枝蓮堿A |
CAS號 | 176520-13-1 |
分子式 | C32H34N2O7 |
分子量 | 558.62 |
外觀 | White to off-white powder |
儲存條件 | 20°C, protect from light |
Scutebarbatine A shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2. Scutebarbatine A and barbatine A show a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 uM, respectively.
vitro and in vivo antitumor activity of scutebarbatine A on human lung carcinoma A549 cell lines.
PMID: 24968330 PMCID: PMC6270914 DOI: 10.3390/molecules19078740
PMID: 33512038 DOI: 10.1002/jbt.22731