英文名稱 | Rosavin |
---|---|
中文名稱 | 絡(luò)塞維 |
CAS號 | 84954-92-7 |
分子式 | C20H28O10 |
分子量 | 428.43 |
外觀 | White to yellow powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
英文名稱 | Rosavin |
---|---|
中文名稱 | 絡(luò)塞維 |
CAS號 | 84954-92-7 |
分子式 | C20H28O10 |
分子量 | 428.43 |
外觀 | White to yellow powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Rosavin, an orally bioactive phenylpropanoid from Rhodiola rosea L. (RRL), is an adaptogen that enhances the body’s response to environmental stress. Rosavin significantly influences bone tissue metabolism by inhibiting osteoclastogenesis and promoting osteoblast differentiation, also impacts various diseases, demonstrating antidepressant, adaptogenic, and anxiolytic effects in mouse models. Additionally, Rosavin improves survival, reducing intestinal damage in irradiated rats and Ischemia-reperfusion(I/R)-induced cerebral injury in vivo by regulating inflammation and oxidative stress, making it a promising candidate for research in radiation-induced intestinal injury, I/R-induced cerebral injury and osteoporosis.
PMID: 37254848 DOI: 10.1111/1440-1681.13781
The Role of Rosavin in the Pathophysiology of Bone Metabolism[J].
Int J Mol Sci. 2024 Feb 9;25(4):2117.
PMID: 38339153 PMCID: PMC10856478 DOI: 10.3390/ijms25031875