英文名稱 | Resveratrol | trans-Resveratrol | SRT501 |
---|---|
中文名稱 | 白藜蘆醇 |
CAS號 | 501-36-0 |
分子式 | C14H12O3 |
分子量 | 228.24 |
外觀 | White to off-white powder |
儲存條件 | -20°C |
英文名稱 | Resveratrol | trans-Resveratrol | SRT501 |
---|---|
中文名稱 | 白藜蘆醇 |
CAS號 | 501-36-0 |
分子式 | C14H12O3 |
分子量 | 228.24 |
外觀 | White to off-white powder |
儲存條件 | -20°C |
Resveratrol has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases(LOX, IC50=2.7 μM), kinases, sirtuins and other proteins. It has anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol induces mitophagy/autophagy and autophagy-dependent apoptosis.
Resveratrol: one molecule, many targets
PMID: 18421779 DOI: 10.1002/iub.47
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
PMID: 12939617 DOI: 10.1038/nature01960
Therapeutic potential of resveratrol: the in vivo evidence
PMID: 16732220 DOI: 10.1038/nrd2060