英文名稱 | TW-37 |
---|---|
中文名稱 | TW-37 | N-[4-(2-叔丁基苯磺?;?苯基]-2,3,4-三羥基-5-(2-異丙基芐基)苯甲酰胺 |
CAS號 | 877877-35-5 |
分子式 | C33H35NO6S |
分子量 | 573.70 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | TW-37 |
---|---|
中文名稱 | TW-37 | N-[4-(2-叔丁基苯磺?;?苯基]-2,3,4-三羥基-5-(2-異丙基芐基)苯甲酰胺 |
CAS號 | 877877-35-5 |
分子式 | C33H35NO6S |
分子量 | 573.70 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM in cell-free assays, respectively.
Antiangiogenic effect of TW37, a small-molecule inhibitor of Bcl-2.
PMID: 16951185 DOI: 10.1158/0008-5472.CAN-05-3691
PMID: 17404107 DOI: 10.1158/1078-0432.CCR-06-1574