英文名稱 | Crenolanib | CP-868596 | ARO 002 |
---|---|
中文名稱 | 克萊拉尼 |
CAS號 | 670220-88-9 |
分子式 | C26H29N5O2 |
分子量 | 443.54 |
外觀 | Off-white to light green powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Crenolanib | CP-868596 | ARO 002 |
---|---|
中文名稱 | 克萊拉尼 |
CAS號 | 670220-88-9 |
分子式 | C26H29N5O2 |
分子量 | 443.54 |
外觀 | Off-white to light green powder |
儲(chǔ)存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Crenolanib is a potent and selective inhibitor of wild-type and mutant isoforms of the class III receptor tyrosine kinases and with Kds of 0.74 nM and 2.1 nM/3.2 nM, respectively.
PMID: 25328409 PMCID: PMC4196792 DOI: 10.2147/OTT.S68773
PMID: 22745105 DOI: 10.1158/1078-0432.CCR-12-0625
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