英文名稱 | Stavudine (d4T) |
---|---|
中文名稱 | 司他夫定 |
CAS號 | 3056-17-5 |
分子式 | C10H12N2O4 |
分子量 | 224.21 |
外觀 | White to light yellow powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
英文名稱 | Stavudine (d4T) |
---|---|
中文名稱 | 司他夫定 |
CAS號 | 3056-17-5 |
分子式 | C10H12N2O4 |
分子量 | 224.21 |
外觀 | White to light yellow powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine has activity against HIV-1 and HIV-2. Stavudine also inhibits the replication of mitochondrial DNA (mtDNA). Stavudine reduces NLRP3 inflammasome activation and modulates Amyloid-β autophagy. Stavudine induces apoptosis.
PMID: 15577645 DOI: 10.1097/00002030-200411050-00004
PMID: 8568296 DOI: 10.1093/infdis/173.2.355