英文名稱 | PD 169316 |
---|---|
中文名稱 | PD 169316 |
CAS號 | 152121-53-4 |
分子式 | C20H13FN4O2 |
分子量 | 360.34 |
外觀 | Light yellow to yellow powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
英文名稱 | PD 169316 |
---|---|
中文名稱 | PD 169316 |
CAS號 | 152121-53-4 |
分子式 | C20H13FN4O2 |
分子量 | 360.34 |
外觀 | Light yellow to yellow powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
PD 169316 is a potent, selective and cell-permeable p38 MAP kinase inhibitor with IC50 of 89 nM. PD169316 abrogates signaling initiated by both TGFbeta and Activin A. PD169316 shows antiviral activity against Enterovirus71.
PD169316, a specific p38 inhibitor, shows antiviral activity against Enterovirus71
PMID: 28545002 DOI: 10.1016/j.virol.2017.05.012
PMID: 27894083 PMCID: PMC5349970 DOI: 10.18632/oncotarget.13498
p38 and p42/44 MAPKs differentially regulate progesterone receptor A and B isoform stabilization.
PMID: 21816898 PMCID: PMC3551571 DOI: 10.1210/me.2011-1042
PMID: 14521923 DOI: 10.1016/j.bbrc.2003.09.021