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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
1 mg	3-5days	￥766.00	登錄后可見	- +
5 mg	3-5days	￥1908.00	登錄后可見	- +

規(guī)格

庫存

目錄價

會員專享價

數(shù)量

1 mg

3-5days

￥766.00

登錄后可見

- +

5 mg

3-5days

￥1908.00

登錄后可見

- +

基本信息

英文名稱	ZYF0033 \| HPK1-IN-22
中文名稱	ZYF0033 \| HPK1-IN-22
CAS號	2380300-79-6
分子式	C26H30N4O2S
分子量	462.61
外觀	White to off-white powder
儲存條件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

產(chǎn)品詳情

HPK1-IN-22 (compound ZYF0033) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 less than 10 nM based on the phosphorylation inhibition of MBP protein. HPK1-IN-22 decreases the phosphorylation of SLP76 (serine 376). HPK1-IN-22 promotes anticancer immune responses.HPK1-IN-22 inhibits tumor growth and caused increases intratumoral infiltration of DCs, NK cells, and CD107a+CD8+ T cells but decreased infiltration of regulatory T cells, PD-1+CD8+ T cells, TIM-3+CD8+ T cells, and LAG3+CD8+ T cells in the 4T-1 syngeneic mouse model.

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CL2817

ZYF0033 | HPK1-IN-22

2380300-79-6 98+% 3-5days

￥766.00 1 mg

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ZYF0033 | HPK1-IN-22

ZYF0033 | HPK1-IN-22

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