英文名稱 | Azacitidine | 5-Azacytidine | 5-AzaC | Ladakamycin |
---|---|
中文名稱 | 阿扎胞苷 | 5-氮雜胞苷 |
CAS號 | 320-67-2 |
分子式 | C8H12N4O5 |
分子量 | 244.20 |
外觀 | White to yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Azacitidine | 5-Azacytidine | 5-AzaC | Ladakamycin |
---|---|
中文名稱 | 阿扎胞苷 | 5-氮雜胞苷 |
CAS號 | 320-67-2 |
分子式 | C8H12N4O5 |
分子量 | 244.20 |
外觀 | White to yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
5-Azacytidine (Azacitidine; 5-AzaC; Ladakamycin) is a nucleoside analogue of cytidine that specifically inhibits DNA methylation. 5-Azacytidine is incorporated into DNA to covalently trap DNA methyltransferases and contributes to reverse epigenetic changes. 5-Azacytidine induces cell autophagy.
PMID: 12154409 DOI: 10.1038/sj.onc.1205699
PMID: 31214275 PMCID: PMC6535830 DOI: 10.1155/2019/1523140