英文名稱 | A 83-01 | A-83-01 |
---|---|
中文名稱 | A 83-01 | A-83-01 |
CAS號(hào) | 909910-43-6 |
分子式 | C25H19N5S |
分子量 | 421.52 |
外觀 | Off-white to light yellow powder |
儲(chǔ)存條件 | -20°C, protect from light, stored under nitrogen |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專享價(jià) | 數(shù)量 | |
---|---|---|---|---|---|
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英文名稱 | A 83-01 | A-83-01 |
---|---|
中文名稱 | A 83-01 | A-83-01 |
CAS號(hào) | 909910-43-6 |
分子式 | C25H19N5S |
分子量 | 421.52 |
外觀 | Off-white to light yellow powder |
儲(chǔ)存條件 | -20°C, protect from light, stored under nitrogen |
A-83-01 is a potent inhibitor of TGF-β type I receptor (ALK5-TD) with IC50 of 12 nM. A-83-01 also inhibits the transcription induced by activin/nodal type I receptor (ALK4-TD) and nodal type I receptor (ALK7-TD) with IC50 of 45 nM and 7.5 nM, respectively.
Solutions are unstable and should be fresh-prepared.