英文名稱 | Strontium Ranelate |
---|---|
中文名稱 | 雷尼酸鍶; 雷奈酸鍶 |
CAS號 | 135459-87-9 |
分子式 | C12H6N2O8SSr2 |
分子量 | 513.49 |
外觀 | Light yellow to yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Strontium Ranelate |
---|---|
中文名稱 | 雷尼酸鍶; 雷奈酸鍶 |
CAS號 | 135459-87-9 |
分子式 | C12H6N2O8SSr2 |
分子量 | 513.49 |
外觀 | Light yellow to yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis. Studies indicate it can also slow the course of osteoarthritis of the knee. The drug is unusual in that it both increases deposition of new bone by osteoblasts and reduces the resorption of bone by osteoclasts. It is therefore promoted as a "dual action bone agent" (DABA) indicated for use in the treatment of severe osteoporosis.
Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation.
PMID: 16735840 DOI: 10.1097/01.bor.0000229522.89546.7b
PMID: 17945546 DOI: 10.1016/j.bone.2007.08.043