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尼日利亞菌素鈉鹽

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Nigericin Sodium Salt

產(chǎn)品編號:CL2229 CAS No.:28643-80-3 MDLNo: 分子式:C40H67NaO11 分子量:746.94
規(guī)格 庫存 目錄價 會員專享價 數(shù)量
5 mg In-stock ¥466.00 登錄后可見
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10 mg In-stock ¥766.00 登錄后可見
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基本信息
英文名稱 Nigericin Sodium Salt
中文名稱尼日利亞菌素鈉鹽
CAS號28643-80-3
分子式C40H67NaO11
分子量746.94
外觀White to off-white powder
儲存條件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Nigericin is a cationic ionophore that inhibits Golgi function and suppresses growth of gram positive bacteria. It also prevents viral activation and triggers activation of the NALP3 inflammasome. Nigericin acts as an H+, K+, Pb2+ ionophore. Most commonly it is an antiporter of H+ and K+. In the past nigericin was used as an antibiotic active against gram positive bacteria. It inhibits the Golgi functions in Eukaryotic cells. Its ability to induce K+ efflux also makes it a potent activator of the NLRP3 inflammasome.

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