英文名稱 | Mobocertinib Succinate (TAK-788 Succinate) |
---|---|
中文名稱 | 莫博替尼琥珀酸鹽 |
CAS號 | 2389149-74-8 |
分子式 | C36H45N7O8 |
分子量 | 703.78 |
外觀 | White to yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Mobocertinib Succinate (TAK-788 Succinate) |
---|---|
中文名稱 | 莫博替尼琥珀酸鹽 |
CAS號 | 2389149-74-8 |
分子式 | C36H45N7O8 |
分子量 | 703.78 |
外觀 | White to yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Mobocertinib succinate is an investigational TKI with potent, selective preclinical activity against activating EGFR and HER2 mutations, including exon 20 insertions. TAK-788 exhibits antitumor activity in pts with EGFR exon 20 insertions with an AE profile consistent with other EGFR TKIs.