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米托蒽醌二鹽酸鹽/鹽酸米托蒽醌

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Mitoxantrone Dihydrochloride; Mitoxantrone 2HCl

產(chǎn)品編號(hào):CL2210A CAS No.:70476-82-3 MDLNo: 分子式:C22H29ClN4O6.2HCl 分子量:517.4
規(guī)格 庫(kù)存 目錄價(jià) 會(huì)員專享價(jià) 數(shù)量
50 mg In-stock ¥260.00 登錄后可見
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100 mg In-stock ¥400.00 登錄后可見
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250 mg In-stock ¥860.00 登錄后可見
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500 mg In-stock ¥1360.00 登錄后可見
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基本信息
英文名稱 Mitoxantrone Dihydrochloride; Mitoxantrone 2HCl
中文名稱米托蒽醌二鹽酸鹽/鹽酸米托蒽醌
CAS號(hào)70476-82-3
分子式C22H29ClN4O6.2HCl
分子量517.4
外觀Dark blue powder
儲(chǔ)存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

 Mitoxantrone is an anthraquinone that intercalates in DNA and inhibits topoisomerase II (IC50 = 5.3 μM), thus inhibiting cell proliferation. It also inhibits HIV-1 integrase (IC50 = 3.8 μM). Mitoxantrone is exported from cells in an ATP- and glutathione-dependent manner by multidrug resistance protein-1.4 Formulations containing mitoxantrone have been used in the treatment of cancer and multiple sclerosis.

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