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扎西他濱

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Zalcitabine (ddC; Dideoxycytidine; 2',3'-Dideoxycytidine)

產(chǎn)品編號：CL2159 CAS No.：7481-89-2 MDLNo： 分子式：C9H13N3O3 分子量：211.22
規(guī)格 庫存 目錄價 會員專享價 數(shù)量
100 mg In-stock ￥600.00 登錄后可見
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250 mg In-stock ￥960.00 登錄后可見
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500 mg 3-5days ￥1536.00 登錄后可見
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基本信息
英文名稱 Zalcitabine (ddC; Dideoxycytidine; 2',3'-Dideoxycytidine)
中文名稱扎西他濱
CAS號7481-89-2
分子式C9H13N3O3
分子量211.22
外觀White to light yellow powder
儲存條件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Zalcitabine (trade name Hivid) is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI). It is an antiviral pyrimidine nucleoside analogue effective against HIV replication. 2′,3′-Dideoxycytidine, when activated to its triphosphate, is incorporated into DNA by HIV-1 RT (HIV-1 reverse transcriptase), causing DNA chain termination and viral replication. Zalcitabine was the third antiretroviral to be approved by the Food and Drug Administration (FDA) for the treatment of HIV/AIDS. It is used as part of a combination regimen. Zalcitabine appears less potent than some other nucleoside RTIs, has an inconvenient three-times daily frequency and is associated with serious adverse events. For these reasons it is now rarely used to treat human immunodeficiency virus (HIV), and it has even been removed from pharmacies entirely in some countries.

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