英文名稱 | Dasatinib |
---|---|
中文名稱 | 達沙替尼 |
CAS號 | 302962-49-8 |
分子式 | C22H26ClN7O2S |
分子量 | 488.01 |
外觀 | White, off-white to pale yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Dasatinib |
---|---|
中文名稱 | 達沙替尼 |
CAS號 | 302962-49-8 |
分子式 | C22H26ClN7O2S |
分子量 | 488.01 |
外觀 | White, off-white to pale yellow powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.