英文名稱 | SB-505124 |
---|---|
中文名稱 | SB-505124 |
CAS號 | 694433-59-5 |
分子式 | C20H21N3O2 |
分子量 | 335.40 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | SB-505124 |
---|---|
中文名稱 | SB-505124 |
CAS號 | 694433-59-5 |
分子式 | C20H21N3O2 |
分子量 | 335.40 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
SB-505124 is a selective inhibitor of TGF-β Receptor type I receptors (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
PMID: 14978253 DOI: 10.1124/mol.65.3.744
PMID: 21031133 PMCID: PMC2956700