英文名稱 | Eribulin | B1939 | E7389 | ER-086526 |
---|---|
中文名稱 | 艾日布林 |
CAS號(hào) | 253128-41-5 |
分子式 | C40H59NO11 |
分子量 | 729.90 |
外觀 | White to off-white powder |
儲(chǔ)存條件 | -20°C, protect from light, stored under nitrogen |
規(guī)格 | 庫(kù)存 | 目錄價(jià) | 會(huì)員專享價(jià) | 數(shù)量 | |
---|---|---|---|---|---|
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英文名稱 | Eribulin | B1939 | E7389 | ER-086526 |
---|---|
中文名稱 | 艾日布林 |
CAS號(hào) | 253128-41-5 |
分子式 | C40H59NO11 |
分子量 | 729.90 |
外觀 | White to off-white powder |
儲(chǔ)存條件 | -20°C, protect from light, stored under nitrogen |
Eribulin (E7389) is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules.
Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase.
PMID: 18645010 PMCID: PMC2562299 DOI: 10.1158/1535-7163.MCT-08-0095
Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability.
PMID: 20030375 PMCID: PMC2846717 DOI: 10.1021/bi901810u
Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo.
PMID: 30719211 PMCID: PMC6349434 DOI: 10.18632/oncotarget.26536
PMID: 21127197 DOI: 10.1158/0008-5472.CAN-10-1874