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依托考昔

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Etoricoxib (MK-663; MK-0663)

產(chǎn)品編號:CL1843 CAS No.:202409-33-4 MDLNo: 分子式:C18H15ClN2O2S 分子量:358.84
規(guī)格 庫存 目錄價(jià) 會員專享價(jià) 數(shù)量
25 mg 3-5days ¥400.00 登錄后可見
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50 mg 3-5days ¥650.00 登錄后可見
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100 mg 3-5days ¥850.00 登錄后可見
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基本信息
英文名稱 Etoricoxib (MK-663; MK-0663)
中文名稱依托考昔
CAS號202409-33-4
分子式C18H15ClN2O2S
分子量358.84
外觀Light yellow to yellow powder
儲存條件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
產(chǎn)品詳情

Etoricoxib (also known as MK-0663) is a non-steroidal anti-inflammatory drgu (NSAID) which acts as a selective and orally bioactive COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood. Etoricoxib is a synthetic NSAID with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib binds specifically to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.

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