英文名稱 | SB 271046 |
---|---|
中文名稱 | SB 271046 |
CAS號 | 209481-20-9 |
分子式 | C20H22ClN3O3S2 |
分子量 | 451.99 |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
英文名稱 | SB 271046 |
---|---|
中文名稱 | SB 271046 |
CAS號 | 209481-20-9 |
分子式 | C20H22ClN3O3S2 |
分子量 | 451.99 |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
SB 271046 is a potent, selective and orally active 5-HT6 receptor antagonist with a pKi of 8.92-9.09. SB 271046 show >200-fold selective for the 5-HT6 receptor over other receptors, binding sites and ion channels. SB 271046 has anticonvulsant activity.
Characterization of SB-271046: a potent, selective and orally active 5-HT(6) receptor antagonist.
PMID: 10928964 PMCID: PMC1572216 DOI: 10.1038/sj.bjp.0703457