英文名稱 | Fulvestrant | ICI 182780 | ZD 9238 | ZM 182780 |
---|---|
中文名稱 | 氟維司群 |
CAS號 | 129453-61-8 |
分子式 | C32H47F5O3S |
分子量 | 606.77 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
英文名稱 | Fulvestrant | ICI 182780 | ZD 9238 | ZM 182780 |
---|---|
中文名稱 | 氟維司群 |
CAS號 | 129453-61-8 |
分子式 | C32H47F5O3S |
分子量 | 606.77 |
外觀 | White to off-white powder |
儲存條件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Fulvestrant is an estrogen receptor (ER) antagonist with IC50 of 0.94 nM in a cell-free assay. Fulvestrant also induces autophagy and apoptosis and has antitumor activity.
Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action.
PMID: 15094757 PMCID: PMC2750773 DOI: 10.1038/sj.bjc.6601629
PMID: 26666173 PMCID: PMC4678692 DOI: 10.1186/s12943-015-0480-4