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沃諾拉贊鹽酸鹽

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Vonoprazan hydrochloride | TAK-438 hydrochloride

產(chǎn)品編號(hào):CL1412B CAS No.:1957202-44-6 MDLNo: 分子式:C17H16FN3O2S·HCl 分子量:381.85 | 345.39 (Free)
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基本信息
英文名稱(chēng) Vonoprazan hydrochloride | TAK-438 hydrochloride
中文名稱(chēng)沃諾拉贊鹽酸鹽
CAS號(hào)1957202-44-6
分子式C17H16FN3O2S·HCl
分子量381.85 | 345.39 (Free)
儲(chǔ)存條件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
產(chǎn)品詳情

Vonoprazan hydrochloride, a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan hydrochloride inhibits H+, K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan hydrochloride is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan hydrochloride can be used for eradication of Helicobacter pylori.



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