英文名稱 | Terbinafine |TDT 067 |
---|---|
中文名稱 | 特比萘芬 |
CAS號 | 91161-71-6 |
分子式 | C21H25N |
分子量 | 291.43 |
外觀 | White to yellow powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
英文名稱 | Terbinafine |TDT 067 |
---|---|
中文名稱 | 特比萘芬 |
CAS號 | 91161-71-6 |
分子式 | C21H25N |
分子量 | 291.43 |
外觀 | White to yellow powder |
儲存條件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.