英文名稱 | IRAK-1-4 Inhibitor I | IRAK-1/4 Inhibitor |
---|---|
中文名稱 | IRAK-1-4抑制劑I | 1-(2-(4-嗎啉基)乙基)-2-(3-硝基苯甲酰基)苯并咪唑 | N-(2-嗎啉基乙基)-2-(3-硝基苯甲酰胺)-苯并咪唑 |
CAS號 | 509093-47-4 |
分子式 | C20H21N5O4 |
分子量 | 395.41 |
MDL | MFCD09752602 |
英文名稱 | IRAK-1-4 Inhibitor I | IRAK-1/4 Inhibitor |
---|---|
中文名稱 | IRAK-1-4抑制劑I | 1-(2-(4-嗎啉基)乙基)-2-(3-硝基苯甲酰基)苯并咪唑 | N-(2-嗎啉基乙基)-2-(3-硝基苯甲酰胺)-苯并咪唑 |
CAS號 | 509093-47-4 |
分子式 | C20H21N5O4 |
分子量 | 395.41 |
MDL | MFCD09752602 |
IRAK-1-4 Inhibitor I is an inhibitor of interleukin-1 receptor-associated kinase 1/4 (IRAK 1/4) with IC50s of 0.2 μM and 0.3 μM, respectively.
Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
PMID: 16563752 DOI: 10.1016/j.bmcl.2006.03.020
Bcl10 mediates LPS-induced activation of NF-kappaB and IL-8 in human intestinal epithelial cells.
PMID: 17540779 DOI: 10.1152/ajpgi.00149.2007