英文名稱 | Omadacycline | PTK 0796 | Amadacycline |
---|---|
中文名稱 | 奧瑪環(huán)素 |
CAS號(hào) | 389139-89-3 |
分子式 | C29H40N4O7 |
分子量 | 556.65 |
外觀 | Light yellow to yellow powder |
儲(chǔ)存條件 | -20°C, sealed storage, away from moisture and light |
英文名稱 | Omadacycline | PTK 0796 | Amadacycline |
---|---|
中文名稱 | 奧瑪環(huán)素 |
CAS號(hào) | 389139-89-3 |
分子式 | C29H40N4O7 |
分子量 | 556.65 |
外觀 | Light yellow to yellow powder |
儲(chǔ)存條件 | -20°C, sealed storage, away from moisture and light |
Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections.
Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent.
PMID: 31970713 DOI: 10.1007/s40265-020-01257-4
In vitro and in vivo antibacterial activities of omadacycline, a novel aminomethylcycline.
PMID: 24295985 PMCID: PMC3910882 DOI: 10.1128/AAC.01242-13
Omadacycline: A Newly Approved Antibacterial from the Class of Tetracyclines.
PMID: 31010063 PMCID: PMC6630996 DOI: 10.3390/ph12020063