達格列凈

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Dapagliflozin (BMS-512148)

產品編號：CL1127 CAS No.：461432-26-8 MDLNo： 分子式：C21H25ClO6 分子量：408.87

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規(guī)格	庫存	目錄價	會員專享價	數(shù)量
500 mg	In-stock	￥488.00	登錄后可見	- +
1 g	3-5days	￥788.00	登錄后可見	- +

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基本信息
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基本信息

英文名稱	Dapagliflozin (BMS-512148)
中文名稱	達格列凈
CAS號	461432-26-8
分子式	C21H25ClO6
分子量	408.87
外觀	White to off-white powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產品詳情

Dapagliflozin (formerly known as BMS-512148; trade names Farxiga in the US and Forxiga in the EU) is a potent and selective hSGLT2 (sodium-glucose transport proteins) inhibitor with anti-diabetic activity. It inhibits hSGLT2 with an EC50 of 1.1 nM, and exhibits1200-fold selectivity over hSGLT1. Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2) which are responsible for at least 90% of the glucose reabsorption in the kidney. Urine is the means by which blood glucose is expelled when this transporter mechanism is blocked.

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CL1127

達格列凈

461432-26-8 98+% In-stock

￥488.00 500 mg