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規(guī)格	庫存	目錄價	會員專享價	數量
5 mg	In-stock	￥600.00	登錄后可見	- +
10 mg	In-stock	￥800.00	登錄后可見	- +
25 mg	In-stock	￥1800.00	登錄后可見	- +
50 mg	In-stock	￥3000.00	登錄后可見	- +

規(guī)格

庫存

目錄價

會員專享價

數量

5 mg

In-stock

￥600.00

登錄后可見

- +

10 mg

In-stock

￥800.00

登錄后可見

- +

25 mg

In-stock

￥1800.00

登錄后可見

- +

50 mg

In-stock

￥3000.00

登錄后可見

- +

基本信息

英文名稱	RepSox (E-616452; SJN 2511;ALK5 Inhibitor II) \| 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
中文名稱	2-[3-(6-甲基-2-吡啶基)-1H-吡唑-4-基]-1,5-萘啶
CAS號	446859-33-2
分子式	C17H13N5
分子量	287.32
外觀	Light brown to yellow powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

產品詳情

ALK5 inhibitor II is a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-β cellular assay, and ALK5 binding in HepG2 cells, respectively). This inhibitor demonstrated less potent activity (IC50s > 16 μM) when tested against a panel of 9 related kinases, including p38 MAPK and GSK3. At 25 μM, this compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription.

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CL1007

2-[3-(6-甲基-2-吡啶基)-1H-吡唑-4-基]-1,5-萘啶

446859-33-2 98+% In-stock

￥600.00 5 mg

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2-[3-(6-甲基-2-吡啶基)-1H-吡唑-4-基]-1,5-萘啶

RepSox (E-616452; SJN 2511;ALK5 Inhibitor II) | 2-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine

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